Posts tagged: trial
Phase I clinical trial shows drug shrinks melanoma brain metastases
An experimental drug targeting a common mutation in melanoma successfully shrank tumors that spread to the brain in nine out of 10 patients in part of an international phase I clinical trial report.
Children with cancer have complete responses in a COG phase 1 trial: Pills zero in on abnormal genes that drive specific cancers
A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
Biased evidence? Researchers challenge post-marketing drug trial practices
Bioethicists argue that current research ethics frameworks do not flag drug trials that, while not putting patients at risk, produce biased evidence. As an example, they point to phase IV research -- when pharmaceutical companies test drugs and devices that have been approved for marketing.
Next-generation ‘epigenetic’ cancer pill shown to be safe in phase I trial
Scientists have shown that a brand new type of cancer pill that exploits the emerging field of epigenetics is safe for human use, according to Phase I trial results.
Pill reduced number of multiple sclerosis lesions in Phase II trial
An investigational oral drug called ONO-4641 reduced the number of lesions in people with multiple sclerosis, according to the results of a phase two clinical trial.
New class of platelet blockers proves effective in phase III trial, study suggests
Adding vorapaxar, an investigational platelet blocker, to standard antiplatelet therapy significantly reduces the risk of recurrent cardiovascular events in patients with known atherosclerosis, a hardening and narrowing of the arteries, according to new research.
Clinical trial examines antioxidant effects for Alzheimer’s disease on cerebrospinal fluid biomarkers
An antioxidant combination of vitamin E, vitamin C and alpha-lipoic acid was not associated with changes in some cerebrospinal fluid biomarkers related to Alzheimer's disease in a randomized controlled trial, according to a new study.
Biblical Relic Dealer Acquitted in Forgery Trial, Sparking Controversy
A suspected forger is acquitted in Israel.
Energy Producing ‘Aquatic Bicycle Pump’ Trial Forthcoming
A trial version of a machine that can generate electricity from seawater could be in place in one UK city before the end of the year, BBC News reported on Monday.The device in question is the Searaser machine, which Damian Carrington of The Guardian referred to as a sort of ...
Effects of Tamiflu still uncertain, warn experts, as Roche continues to withhold key trial data, according to new report
Two years after pharmaceutical giant Roche promised the British Medical Journal it would release key Tamiflu trial data for independent scrutiny, the safety and effectiveness of this anti-influenza drug remains uncertain, warn experts. A new report by the Cochrane Collaboration says Roche's refusal to provide full access to all its ...
Trial Begins for Witchcraft Torture Killing
A man is accused of killing his girlfriend's brother over suspected witchcraft.