Posts tagged: transplantation
First successful transplantation of a synthetic tissue engineered windpipe
For the first time in history, a patient has been given a new trachea made from a synthetic scaffold seeded with his own stem cells. The patient, a 36-year old man, is well on the way to full recovery from the recent operation in Sweden and is now being discharged ...
Genetic alterations in pig tissue may allow for human transplantation
A sizzling genetic discovery may one day allow pig tissue to be transplanted successfully into humans. Scientists have taken a step forward toward filling the shortage of vital organs for human transplantation. Research has shown that altering or overexpressing human programmed death ligand-1 molecule in endothelial cells of pig arteries ...
Many more lungs suitable for transplantation
Four patients now have new lungs thanks to a purpose-built machine used for the first time. The new machine will contribute to more lung transplants in the long term.
Angioplasty may be feasible for liver transplantation candidates with heart disease
A small, retrospective study determined that percutaneous coronary intervention (PCI) was safe in patients with significant coronary artery disease (CAD) who were referred for liver transplantation. Larger studies are needed to determine the effectiveness of angioplasty in patients with end-stage liver disease (ESLD).
New substance may allow successful transplantation of ‘marginal’ livers
New research raises the possibility that the critically short supply of livers for organ donation could be expanded by treating so-called "marginal" livers with a substance that protects them from damage after being connected to recipients' blood supplies. The report appears in ACS' journal Molecular Pharmaceutics.
New substance may allow successful transplantation of ‘marginal’ livers
New research raises the possibility that the critically short supply of livers for organ donation could be expanded by treating so-called "marginal" livers with a substance that protects them from damage after being connected to recipients' blood supplies.
IL28B Gene Predicts Treatment Outcome for Liver Transplantation Patients
Researchers have found a significant association of IL28B genotypes to interferon-based antiviral treatment outcome, and to graft inflammation caused by hepatitis C virus (HCV). The study determined that the presence of G-allele serves as a marker for severe HCV-induced graft inflammation, as well as a predictor for unsuccessful treatment.
Researchers Work At The Frontiers Of Islet Cell Transplantation
Two studies published in the current issue of Cell Transplantation (19:12) investigate frontiers of islet cell transplantation for treating diabetes. Researchers in Milan, Italy re-examine the role of bone marrow stem cells in diabetic therapy and islet cell regeneration and Canadian researchers offer improved strategies for optimizing pancreatic islet culture ...
Patients Infected with HIV have Higher Drop-Out Rate for Liver Transplantation
Researchers have determined that infection with human immunodeficiency virus (HIV) impaired results of transplant surgery for liver cancer, with more HIV infected patients dropping off the transplantation wait list. The team found that overall survival and recurrence-free survival was not impacted following liver transplantation in patients with controlled HIV disease.
Scientists Grow Human Liver Tissue to be Used for Transplantation
A new study reports on the success of growing human liver cells on resorbable scaffolds made from material similar to surgical sutures. Researchers suggest that this liver tissue could be used in place of donor organs during liver transplantation or during the bridge period until a suitable donor is available ...
Metabolic syndrome found in 52 percent of patients after liver transplantation
Researchers from Israel have determined that more than half of liver transplant recipients develop post-transplantation metabolic syndrome (PTMS), placing them at greater risk for cardiovascular disease. Prior to transplantation only 5 percent of the patients were diagnosed with metabolic syndrome, but rates of obesity, hypertriglyceridemia, hypertension, and diabetes were significantly ...