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Posts tagged: transplantation

Chronic pain is relieved by cell transplantation in lab study

May 23, 2012
Chronic pain, by definition, is difficult to manage, but a new study shows how a cell therapy might one day be used not only to quell some common types of persistent and difficult-to-treat pain, but also to cure the conditions that give rise to them.

Fetal membrane transplantation helps prevent blindness

April 26, 2012
Transplanting tissue from newborn fetal membranes prevents blindness in patients with a devastating disease called Stevens-Johnson syndrome, a new study has found.

Gut microbiota transplantation may prevent development of diabetes and fatty liver disease

April 19, 2012
New data shows the gut microbiota's causal role in the development of diabetes and non-alcoholic fatty liver disease, independent of obesity.

An inside look at face transplantation

December 29, 2011
Researchers describe details of patient preparation, novel design and execution of the operation as well as unique immunosuppression protocol allowing for lowest long-term maintenance drug regimen.

Integrated 3-D imaging facilitates human face transplantation

November 28, 2011
By combining conventional medical imaging with some of the same 3-D modeling techniques used in Hollywood blockbusters, researchers are offering new hope to victims of serious facial injuries who may be candidates for human facial transplants.

Use of low-toxicity conditioning regimen prior to cell transplantation appears promising for older adults with blood, bone marrow cancers

November 2, 2011
Older patients with advanced hematologic malignancies, such as leukemia and lymphoma, who received a conditioning regimen that included minimal-intensity radiation therapy prior to allogeneic (genetically different) hematopoietic cell transplantation (HCT; receipt of bone marrow or stem cells transplant) had survival and progression-free survival outcomes suggesting that this treatment approach may ...

Age no longer a barrier to stem cell transplantation for older patients

November 2, 2011
Age alone no longer should be considered a defining factor when determining whether an older patient with blood cancer is a candidate for stem cell transplantation. That's the conclusion of the first study summarizing long-term outcomes from a series of prospective clinical trials of patients age 60 and over who ...

Lab-made skin cells will aid transplantation, cancer, drug discovery research, say scientists

October 26, 2011
Researchers have found a way to create melanocytes from mouse tail cells using embryonic stem cell-like intermediates called inducible pluripotent (iPS) cells. They converted mouse tail-tip fibroblasts into iPS cells, producing pluripotent cells similar to embryonic stem cells, but without the concomitant ethical issues.

Researchers devise index for predicting long-term survival after liver re-transplantation

September 29, 2011
Researchers have identified eight risk factors for potential re-transplantation failure and, using mathematical modeling, developed a risk scoring system ranging from 0 to 12 to gauge the risk of re-transplantation failure.

Living donor liver transplantation improves survival over deceased donor transplants

September 27, 2011
New research shows liver transplantation candidates without hepatocellular carcinoma (HCC) derive a greater survival benefit from a living donor liver transplant (LDLT) than waiting for a deceased donor liver transplant (DDLT).

Worse postoperative outcomes for critically ill patients bridged to urgent heart transplantation with VADs than with conventional therapy, study suggests

August 28, 2011
Postoperative outcomes of severe heart failure patients bridged with short-term VADs to urgent (~ status UNOS 1A) heart transplantation are significantly worse than those of patients bridged with conventional support, recent data suggest.

Bone marrow transplantation may increase cancer resistance in patients, study suggests

August 25, 2011
Bone marrow transplantation with genetically modified cells may prolong the period of cancer-free survival, suggests a new study.