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Posts tagged: transplantation

An inside look at face transplantation

December 29, 2011
Researchers describe details of patient preparation, novel design and execution of the operation as well as unique immunosuppression protocol allowing for lowest long-term maintenance drug regimen.

Integrated 3-D imaging facilitates human face transplantation

November 28, 2011
By combining conventional medical imaging with some of the same 3-D modeling techniques used in Hollywood blockbusters, researchers are offering new hope to victims of serious facial injuries who may be candidates for human facial transplants.

Use of low-toxicity conditioning regimen prior to cell transplantation appears promising for older adults with blood, bone marrow cancers

November 2, 2011
Older patients with advanced hematologic malignancies, such as leukemia and lymphoma, who received a conditioning regimen that included minimal-intensity radiation therapy prior to allogeneic (genetically different) hematopoietic cell transplantation (HCT; receipt of bone marrow or stem cells transplant) had survival and progression-free survival outcomes suggesting that this treatment approach may ...

Age no longer a barrier to stem cell transplantation for older patients

November 2, 2011
Age alone no longer should be considered a defining factor when determining whether an older patient with blood cancer is a candidate for stem cell transplantation. That's the conclusion of the first study summarizing long-term outcomes from a series of prospective clinical trials of patients age 60 and over who ...

Lab-made skin cells will aid transplantation, cancer, drug discovery research, say scientists

October 26, 2011
Researchers have found a way to create melanocytes from mouse tail cells using embryonic stem cell-like intermediates called inducible pluripotent (iPS) cells. They converted mouse tail-tip fibroblasts into iPS cells, producing pluripotent cells similar to embryonic stem cells, but without the concomitant ethical issues.

Researchers devise index for predicting long-term survival after liver re-transplantation

September 29, 2011
Researchers have identified eight risk factors for potential re-transplantation failure and, using mathematical modeling, developed a risk scoring system ranging from 0 to 12 to gauge the risk of re-transplantation failure.

Living donor liver transplantation improves survival over deceased donor transplants

September 27, 2011
New research shows liver transplantation candidates without hepatocellular carcinoma (HCC) derive a greater survival benefit from a living donor liver transplant (LDLT) than waiting for a deceased donor liver transplant (DDLT).

Worse postoperative outcomes for critically ill patients bridged to urgent heart transplantation with VADs than with conventional therapy, study suggests

August 28, 2011
Postoperative outcomes of severe heart failure patients bridged with short-term VADs to urgent (~ status UNOS 1A) heart transplantation are significantly worse than those of patients bridged with conventional support, recent data suggest.

Bone marrow transplantation may increase cancer resistance in patients, study suggests

August 25, 2011
Bone marrow transplantation with genetically modified cells may prolong the period of cancer-free survival, suggests a new study.

Advance in prevention of diabetes mellitus following kidney transplantation

August 8, 2011
Up to 30 percent of all patients develop diabetes mellitus within the first year after a kidney transplantation. This high rate could soon fall rapidly. An Austrian research team has discovered in the context of a study that preemptive insulin therapy drastically reduces this rate.

First successful transplantation of a synthetic tissue engineered windpipe

July 7, 2011
For the first time in history, a patient has been given a new trachea made from a synthetic scaffold seeded with his own stem cells. The patient, a 36-year old man, is well on the way to full recovery from the recent operation in Sweden and is now being discharged ...

Genetic alterations in pig tissue may allow for human transplantation

June 30, 2011
A sizzling genetic discovery may one day allow pig tissue to be transplanted successfully into humans. Scientists have taken a step forward toward filling the shortage of vital organs for human transplantation. Research has shown that altering or overexpressing human programmed death ligand-1 molecule in endothelial cells of pig arteries ...