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Posts tagged: platelets

From gene to function: Genome wide study into new gene functions in the formation of platelets

November 30, 2011
A new study successfully identifies new genetic variants involved in the formation of platelets and more importantly, defines how genes near these variants affect platelet size and number using a series of biological analyses. This is the largest genome-wide meta-analysis on platelet size and number and involves more than 68,000 ...

Gray Platelet Syndrome: Elusive gene that makes platelets gray identified

July 25, 2011
Researchers have identified an elusive gene responsible for Gray Platelet Syndrome, an extremely rare blood disorder in which only about 50 known cases have been reported. As a result, it is hoped that future cases will be easier to diagnose with a DNA test.

Patients may not have to stop taking anti-platelets for some surgeries, study suggests

December 9, 2010
Despite the common clinical practice among surgeons to discontinue their patients' anti-platelet therapy prior to surgery, a recent study of patients undergoing carotid endarterectomy indicated that this practice may be unnecessary.

Method For Manufacturing Patient-Specific Human Platelets

November 23, 2010
Skin cells from humans can be revamped into pro-clotting cells called platelets, according to a study published on November 22 in the Journal of Experimental Medicine (www.jem.org). Patients with diseases causing thrombocytopenia—platelet deficiency—often require repeated transfusions with platelets obtained from healthy donors.But donor platelet isolation is expensive and labor intensive, ...

Method for manufacturing patient-specific human platelets

November 22, 2010
Skin cells from humans can be revamped into pro-clotting cells called platelets, according to a new study. Patients with diseases causing thrombocytopenia -- platelet deficiency -- often require repeated transfusions with platelets obtained from healthy donors.

Bioengineers create simulator to test blood platelets in virtual heart attacks

June 20, 2010
Bioengineers have trained a computer neural network model to accurately predict how blood platelets would respond to complex conditions found during a heart attack or stroke.

Fewer platelets could be used for some cancer and bone-marrow transplantation patients

March 12, 2010
Physicians may be able to safely lower the platelet dosage in transfusions for cancer and bone-marrow transplant patients without risking increased bleeding, according to new research.

Platelets Can Reproduce During Circulation

January 26, 2010
Discovery challenges understanding of blood cell developmentSALT LAKE CITY – University of Utah researchers led an international team of scientists that is the first to report on the previously undescribed ability of platelets to reproduce themselves in the circulation.

Groundbreaking research shows platelets can reproduce in circulation

January 26, 2010
Scientists have discovered that platelets are able to reproduce themselves in the circulation.

Synthetic platelets halve clotting time

December 17, 2009
Researchers have developed synthetic platelets from biodegradable polymers. In animal models, the synthetics attach to natural platelets and stem bleeding faster than current treatments.

Control of blood clotting by platelets described; provides medical promise

November 27, 2009
Cell fragments called platelets are essential to promote blood clotting. Researchers have now discovered novel molecular interactions at the surface of platelets that control blood clotting.

Potential Risk Identified In Transfusions Of Platelets Before Bone Marrow Transplant

August 14, 2009
A larger number of platelet transfusions given before a bone marrow transplant to treat bone marrow failure syndromes correlates with a greater risk of transplant rejection. A model system in mice shows that platelet transfusions can increase the risk of later bone marrow transplant rejection, even when donor and recipient ...