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Posts tagged: normal

Rotational motion of cells plays a critical role in their normal development, researchers find

January 26, 2012
Researchers have discovered a rotational motion that plays a critical role in the ability of breast cells to form the spherical structures in the mammary gland known as acini. This rotation, called "CAMo," for coherent angular motion, is necessary for the cells to form spheres. Otherwise, cells undergo random motion, ...

Gene crucial to normal development of lungs and brain: Discovery may lead to new ways to replace damaged lung tissues with stem cells

January 12, 2012
Scientists have identified a gene that tells cells to develop multiple cilia, tiny hair-like structures that move fluids through the lungs and brain. The finding may help scientists generate new therapies that use stem cells to replace damaged tissues in the lung and other organs.

How normal cells fuel tumor growth

December 21, 2011
A new study has discovered how normal cells in tumors can fuel cancer progression. The study examines what happens when normal cells called fibroblasts in tumors lose an important tumor-suppressor gene. The findings suggest new strategies for controlling tumor growth, they provide insight into the mechanisms that control the co-evolution ...

First analysis of tumor-suppressor interactions with whole genome in normal human cells reveals key differences with cancer cells

November 30, 2011
Scientists investigating the interactions, or binding patterns, of a major tumor-suppressor protein known as p53 with the entire genome in normal human cells have turned up key differences from those observed in cancer cells. The distinct binding patterns reflect differences in the chromatin (the way DNA is packed with proteins), ...

Study evaluates ‘normal range’ systolic bp levels after ischemic stroke and risk of recurrent stroke

November 15, 2011
Among patients who experienced an ischemic stroke, systolic blood pressure levels of less than 120 mm Hg, or higher than 140 mm Hg, were associated with an increased risk of subsequent stroke, according to a new study.

Bridging the gap: Neuroscientists find normal brain communication in people who lack connections between right and left hemispheres

October 20, 2011
Like a bridge that spans a river to connect two major metropolises, the corpus callosum is the main conduit for information flowing between the left and right hemispheres of our brains. Now, neuroscientists have found that people who are born without that link -- a condition called agenesis of the ...

Even high-but-normal blood pressure elevates stroke risk

September 29, 2011
People with prehypertension have a 55 percent higher risk of experiencing a future stroke than people without prehypertension, report researchers in a new meta-analysis of scientific literature.

How normal cells become brain cancers

September 28, 2011
Brain tumor specimens taken from neurosurgery cases have given scientists a new window on the transformation that occurs as healthy brain cells begin to form tumors.

HIV therapies provide near normal lifespan in Africa, study shows

July 19, 2011
The first large-scale analysis of life expectancy outcomes in Africa for HIV patients receiving combination antiretroviral therapy (cART) shows that such patients can expect to live a near normal lifespan. The study also shows significant variance between patient subgroups.

Cancer stem cells recruit normal stem cells to fuel ovarian cancer

July 18, 2011
Researchers have found that a type of normal stem cell fuels ovarian cancer by encouraging cancer stem cells to grow.

Benefit of blood glucose lowering to near-normal levels remains unclear

July 14, 2011
Whether patients with Type 2 diabetes mellitus benefit from attempts to lower their blood glucose levels to near-normal levels through treatment ("intensive blood glucose control") remains an unanswered question. The studies currently available provide indications of a benefit but also of potential harm, researchers say.

A VIP For Normal Brain Development

July 2, 2011
A team of researchers — led by Pierre Gressens, at Inserm U676, Paris, France, and Vincent Lelièvre, at CNRS UPR-3212, Strasbourg, France — has identified a signaling pathway key for normal brain development in the mouse. Of paramount importance, the data generated suggest that environmental factors, including maternal ones, can ...