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Posts tagged: malaria

Modified bone drug kills malaria parasite in mice

February 28, 2012
A chemically altered osteoporosis drug may be useful in fighting malaria, researchers report in a new study. Unlike similar compounds tested against many other parasitic protozoa, the drug readily crosses into the red blood cells of malaria-infected mice and kills the malaria parasite. The drug works at very low concentrations ...

New combo of chemo and well-known malaria drug delivers double punch to tumors

February 19, 2012
Blocking autophagy -- the process of "self-eating" within cells -- is turning out to be a viable way to enhance the effectiveness of a wide variety of cancer treatments. Specifically, blocking the action of an acidic inner cell part, which acts like a stomach and chews up proteins for recycling, ...

How Malaria Parasite Morphs to Sneak Into Body

February 17, 2012
The malaria parasite uses protein girders to transform from a sphere to a banana-shape.

New malaria method could boost drug production

February 16, 2012
German scientists have developed a new way to make a key malaria drug that they say could easily quadruple production and drop the price significantly, increasing the availability of treatment for a disease that kills hundreds of thousands every year.

Ultrasound study provides first direct evidence of effect of malaria on fetal growth

February 10, 2012
A study of almost 3,800 pregnancies has provided the most accurate and direct evidence to date that malaria infection reduces early fetal growth. Low birth weight is the most important risk factor for neonatal mortality in developing countries. The research, carried out on the border of Thailand and Myanmar, highlights ...

Malaria kills nearly twice as many people than previously thought, but deaths declining rapidly

February 3, 2012
Malaria is killing more people worldwide than previously thought -- 1.2 million -- but the number of deaths has fallen rapidly as efforts to combat the disease have ramped up, according to new research. Researchers say that deaths from malaria have been missed by previous studies because of the assumption ...

Research on vitamins could lead to the design of novel drugs to combat malaria

January 27, 2012
New research could lead to the design of more effective drugs to combat malaria. The research will enable scientists to learn more about the nature of the enzymes required for vitamin biosynthesis by the malaria causing pathogen Plasmodium. Vitamins are essential nutrients required in small amounts, the lack of which ...

Fundamental malaria discovery

January 21, 2012
Researchers have made a fundamental discovery in understanding how malaria parasites cause deadly disease.

Tube-wrapped lamp makes malaria drug

January 20, 2012
Continuous flow photochemistry enables critical singlet oxygen hydroperoxidation, raising hopes of cheap artemisinin production

Anti-malaria drug synthesized with the help of oxygen and light

January 17, 2012
In the future it should be possible to produce the best anti-malaria drug, artemisinin, more economically and in sufficient volumes for all patients.

Anti-malaria drug synthesized with the help of oxygen and light

January 17, 2012
The most effective anti-malaria drug can now be produced inexpensively and in large quantities. This means that it will be possible to provide medication for the 225 million malaria patients in developing countries at an affordable price. Researchers at the Max Planck Institute of Colloids and Interfaces in Potsdam and ...

Scientists characterize protein essential to survival of malaria parasite

January 7, 2012
A biology lab has successfully cracked the structure of an enzyme made by Plasmodium falciparum, the parasitical protozoan that causes the most lethal form of malaria. Plasmodium cannot live without the enzyme, which is uses to make cell membrane. Because people don't make this enzyme, it is an ideal target ...