Deep brain stimulation -- also known as DBS -- is effective at improving motor symptoms and quality of life in patients with advanced Parkinson's disease, according to new research.

For children with HIV infection, the FDA approval of the use of raltegravir, an antiretroviral drug that slows the spread of HIV infection, offers a new weapon to treat HIV infection in children.

Many clinical trials in the United States are failing to report their findings in a publicly available database, despite a recent law that compels them to do so, say researchers.

In a study that investigates the challenges of disseminating clinical research findings in peer-reviewed biomedical journals, Yale School of Medicine researchers have found that fewer than half of a sample of trials primarily or partially funded by the National Institutes of Health were published within 30 months of completing the ...

Demographics and clinical factors appear to be associated with survival in patients with Parkinson's disease, and the presence of dementia is associated with a significant increase in mortality, according to a new report.

The American Society of Clinical Oncology has released Clinical Cancer Advances 2011: ASCO's Annual Report on Progress Against Cancer, an independent review of the advances in cancer research that have had the greatest impact on patient care this year. The report also identifies the most promising trends in oncology and ...

Researchers have shown that it is safe to cut and paste together different viruses in an effort to create the ultimate vehicle for gene therapy. In a phase I clinical trial, the investigators found no side effects from using a "chimeric" virus to deliver replacement genes for an essential muscle ...

The American Academy of Orthopaedic Surgeons Board of Directors has recently approved and released an evidence-based clinical practice guideline (CPG) on the treatment of supracondylar humerus fractures.

A clinical trial comparing prasugrel to clopidogrel for patients with high on-clopidogrel platelet reactivity (HCPR) following percutaneous coronary intervention (PCI) was ended early due to relatively few occurrences of cardiac death or myocardial infarction -- the primary endpoint -- at six month follow up.

In a study conducted at 12 university-based research sites, there was wide variation in how best-estimate clinical diagnoses within the autism spectrum were assigned to individual children.

A large, international clinical trial indicates that a vaccine to prevent anal cancer is safe and effective, according to a new study.

Regenerative medicine in spinal cord injuries (SCI) is proving to help the human body create new cell and nerve connections that are severed during this type of injury. A new review provide evidence that supports researchers moving beyond the lab to conduct human clinical trials for stem cells.