Use of a patient's bone marrow cells for treating chronic ischemic heart failure did not result in improvement on most measures of heart function, according to a new study.

Medical researchers have used a bone marrow transplant to replace faulty immune system cells in models of Rett syndrome. The procedure arrested many severe symptoms of the childhood disorder, including abnormal breathing and movement, and extended the lifespan of Rett mouse models. Exploring the function of microglia deficient in the ...

Use of an experimental class of pain drugs has been linked to joint destruction, and the FDA will decide whether trials of the drugs can continue.

Infants with a life-threatening, often fatal, bone condition saw their symptoms improve after use of an experimental therapy.

A chemically altered osteoporosis drug may be useful in fighting malaria, researchers report in a new study. Unlike similar compounds tested against many other parasitic protozoa, the drug readily crosses into the red blood cells of malaria-infected mice and kills the malaria parasite. The drug works at very low concentrations ...

A person has a tumor removed from her femur. A soldier is struck by an improvised explosive device and loses a portion of his tibia. A child undergoes chemotherapy for osteosarcoma but part of the bone dies as a result. Every year, millions of Americans sustain fractures that don't heal ...

Broken bones in humans and animals are painful and often take months to heal. New research shows promise to shorten healing time significantly and revolutionize the course of fracture treatment.

An endocrine hormone used in clinical trials as an anti-obesity and anti-diabetes drug causes significant and rapid bone loss in mice, raising concerns about its safe use, researchers have shown.

The use of bone morphogenetic protein (BMP) for spinal fusion surgery has risen sharply over the past decade, increasing costs with no evidence of improved outcomes, reports a new study.

Researchers have discovered new links between leukemia cells and cells involved in bone formation, offering a fresh perspective on how the blood cancer progresses and raising the possibility that therapies for bone disorders could help in the treatment of leukemia.

The existence of brucellosis, an infectious disease still prevalent today, has now been confirmed in ancient skeletal remains.

It looks like bone. It feels like bone. For the most part, it acts like bone. And it came off an inkjet printer. Researchers have used a 3-D printer to create a bone-like material that can be used in orthopedic procedures, dental work, and to deliver medicine for treating osteoporosis. ...