In the United States, a baby is born with a facial cleft every hour, of every day of the year! Such birth defects result from both gene mutations and environmental insults. PRDM16 is a transcription factor originally described as being aberrantly activated in specific types of leukemia's, and more recently ...

A UNC-led team of scientists has now shown that transcription factors don't act like an 'on-off' switch, but instead can exhibit much more complex binding behavior.

Anyone who's tried a weekend home improvement project knows that to do a job right, you've got to have the right tools. For cells, these "tools" are proteins encoded by genes. The right genes for the job are turned on only in the specific cells where they are needed. And ...

One can now dictate patient observations on the way home from the clinic and view the transcripts the following morning. Calls for "Accessibility anywhere, anytime" have already started rending the air around healthcare, and here is an app that seeks to do just that!

(PhysOrg.com) -- The human genome contains some 3 billion base pairs that are tightly compacted into the nucleus of each cell. If a DNA strand were the thickness of a human hair, the entire human genome would be crammed into a space the size of a softball, but if it ...

Altering the body's metabolism could be an effective treatment for deadly liver cancer, researchers report.

AUGUSTA, Ga. Altering the body's metabolism could be an effective treatment for deadly liver cancer, researchers report. The finding that inhibiting heat shock transcription factor 1, or HSF1, prevents liver cancer in mice also is another wake-up call that a low-fat, healthy diet is an effective ...

Altering the body's metabolism could be an effective treatment for deadly liver cancer, researchers report.

Altering the body's metabolism could be an effective treatment for deadly liver cancer, researchers report. The finding that inhibiting heat shock transcription factor 1, or HSF1, prevents liver cancer in mice also is another wake-up call that a low-fat, healthy diet is an effective cancer deterrent, said Dr. Demetrius Moskophidis, ...

(Georgia Health Sciences University) Altering the body's metabolism could be an effective treatment for deadly liver cancer, researchers report. The finding that inhibiting heat shock transcription factor 1, or HSF1, prevents liver cancer in mice also is another wake-up call that a low-fat, healthy diet is an effective cancer deterrent, ...

Scientists have deciphered the structure of an essential part of Mediator, a complex molecular machine that plays a vital role in regulating the transcription of DNA. The research adds an important link to discoveries that have enabled scientists to gain a deeper understanding of how cells translate genetic information into ...

INDIANAPOLIS Scientists have deciphered the structure of an essential part of Mediator, a complex molecular machine that plays a vital role in regulating the transcription of DNA. The research adds an important link to discoveries that have enabled scientists to gain a deeper understanding of how ...