Posts tagged: selectively
Potential new therapy that kills cancer cells selectively
Researchers have made a drug that helps the immune system to break down cancerous tumors. It has worked on breast, bowel, prostate, ovarian, brain, bladder and liver cancers, while previous studies show it can also be used to fight some blood cancers. If given early, the drug could even be ...
Novel sensor selectively screens single molecules passing through nanopores
A novel type of sensor, based on nanometer-scale pores in a semiconductor membrane, is a step closer to practical use in applications such as analyzing the protein contents of a single cell. Researchers pioneering single-molecule nanopore sensor technology at the Technische Universit-t M-nchen (TUM) have shown its potential through a ...
Protein assassin: Scientists find that the unfolded end of a protein can kill E. coli-like bacteria selectively
When bacteria wage a turf war, some of the combatants have an extra weapon. Certain strains of the bacteria E. coli produce proteins that kill competing E. coli and other like microbes, and researchers from Newcastle University in England have recently discovered something surprising about one of these lethal proteins: ...
Cancer Cells In Mice Starved By Selectively Inhibiting PKM2
Crippling a protein that allows cancer cells to grow when oxygen is scarce causes tumors to regress, according to a study published online in the Journal of Experimental Medicine. An enzyme called PKM2 (M2 isoform of pyruvate kinase) is ramped up in cancer cells, allowing them to generate ...
Selectively inhibiting PKM2 starves cancer cells
Crippling a protein that allows cancer cells to grow when oxygen is scarce causes tumors to regress, according to a study published online on January 23 in the Journal of Experimental Medicine.
Brain Tumors Sensitized To Chemotherapy By Selectively Stopping Glutathione
Brain cancer cells are particularly resistant to chemotherapy - toxins enter the cells, but before the toxins can kill, cancer cells quickly pump them back outside. In fact, brain cancer cells are even better than healthy cells at cleaning themselves. This means that when hit with chemotherapy, healthy cells ...
Selectively stopping glutathione sensitizes brain tumors to chemotherapy
Brain cancer cells are particularly resistant to chemotherapy toxins enter the cells, but before the toxins can kill, cancer cells quickly pump them back outside. In fact, brain cancer cells are even better than healthy cells at cleaning themselves. This means that when hit with chemotherapy, healthy cells ...
Selectively stopping glutathione sensitizes brain tumors to chemotherapy
Brain cancer cells are particularly resistant to chemotherapy toxins enter the cells, but before the toxins can kill, cancer cells quickly pump them back outside. In fact, brain cancer cells are even better than healthy cells at cleaning themselves. This means that when hit with chemotherapy, healthy cells tend ...
Experimental drug selectively destroys blood supply of fat tissue and decreases body fat
Obese rhesus monkeys lost on average 11 percent of their body weight after four weeks of treatment with an experimental drug that selectively destroys the blood supply of fat tissue, a research team led by scientists at The University of Texas MD Anderson Cancer Center reports in Science Translational Medicine.
Novel Compound Selectively Kills Cancer Cells By Blocking Their Response To Oxidative Stress
A cancer cell may seem out of control, growing wildly and breaking all the rules of orderly cell life and death. But amid the seeming chaos there is a balance between a cancer cell's revved-up metabolism and skyrocketing levels of cellular stress. Just as a cancer cell depends on a ...
Scientists discover new class of compounds that selectively block ‘serine hydrolases’
Scientists from The Scripps Research Institute have identified a class of compounds that could be a boon to basic research and drug discovery.