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Posts tagged: pseudomonas

Pseudomonas Aeruginosa Targets Opponents’ Cell Walls And Immunizes Itself Against Its Own Weapons

July 25, 2011
When competing for food and resources, bacteria employ elaborate strategies to keep rival cells at bay. Scientists have now identified a pathway that allows disease-causing bacteria to attack other bacterial cells by breaking down their cell wall. Pseudomonas aeruginosa is a type of bacteria readily found in everyday environments. It ...

Pseudomonas Deploys A Toxin Delivery Machine To Breach Cell Walls Of Rivals Without Hurting Itself

July 21, 2011
Microbiologists have uncovered a sneaky trick by the bacterium Pseudomonas aeruginosa to oust rivals. It deploys a toxin delivery machine to breach cell walls of competitors without hurting itself. Its means of attack helps it survive in the outside environment and may even help it cause infection. P. aeruginosa is ...

Pseudomonas deploys a toxin delivery machine to breach cell walls of rivals without hurting itself

July 20, 2011
Microbiologists have uncovered a sneaky trick by the bacterium Pseudomonas aeruginosa to oust rivals. It deploys a toxin delivery machine to breach cell walls of competitors without hurting itself.

Insmed’s ARIKACE® Demonstrates Sustained Benefit Through Six Cycles Of Treatment For Cystic Fibrosis Patients With Pseudomonas Lung Infections

June 11, 2011
Insmed Incorporated (Nasdaq CM: INSM), a biopharmaceutical company, announced positive data through six treatment cycles (72 weeks total duration) of its Phase 2 clinical trial program for ARIKACE® (liposomal amikacin for inhalation) in cystic fibrosis (CF) patients with Pseudomonas lung infections. The data were presented at the 34th European ...

Intercell Announces Next Steps Of Development For Pseudomonas Vaccine

April 1, 2011
Today Intercell AG (VSE: ICLL) announced that it has agreed with Novartis to advance Intercell's investigational Pseudomonas aeruginosa vaccine into a confirmatory clinical efficacy trial in ventilated ICU (Intensive Care Unit) patients. The planned double blind study is powered to show a clinically meaningful and statistically significant reduction in overall ...

Intercell Reports Positive Results From Its Phase II Pseudomonas Aeruginosa Investigational Vaccine Study for Certain Hospital-Acquired Infections

October 25, 2010
VIENNA, Oct. 25 /- Intercell AG (VSE: ICLL) today announced results from a Phase II clinical trial involving the company's investigational nosocomial vaccine candidate (IC43) against infections with the bacterium Pseudomonas aeruginosa , a leading cause of hospital-acquired infections with increasing antibiotic resistance and hence a very ...

ARIKACE™ Demonstrates Sustained Benefit in Multiple Studies and Over Multiple Cycles of Treatment of Pseudomonas Lung Infections in Cystic Fibrosis Patients

October 21, 2010
MONMOUTH JUNCTION, N.J., Oct. 21 /-Transave, Inc., today reported positive clinical trial results on its lead investigational drug, ARIKACE™ (liposomal amikacin for inhalation), an antibiotic that is entering Phase III development for the treatment of chronic lung infections.  The results demonstrate significant clinical benefit and complete the company's Phase II ...

Life-saving in the bacterial world: How Campylobacter rely on Pseudomonas to infect humans

October 7, 2010
Many a holiday is ruined by food poisoning, frequently caused by the bacterium Campylobacter jejuni. Although Campylobacter infections are rarely life-threatening they are extremely debilitating and have been linked with the development of Guillain-Barré syndrome, one of the leading causes of non-trauma-induced paralysis worldwide.

Life-saving in the bacterial world: How Campylobacter rely on Pseudomonas to infect humans

October 7, 2010
Many a holiday is ruined by food poisoning, frequently caused by the bacterium Campylobacter jejuni . Although Campylobacter infections are rarely life-threatening they are extremely debilitating and have been linked with the development of Guillain-Barr syndrome, one of the leading causes of non-trauma-induced paralysis worldwide. ...

Life-saving in the bacterial world: How Campylobacter rely on Pseudomonas to infect humans

October 7, 2010
The bacterium Campylobacter jejuni is a major cause of food poisoning in humans. Campylobacter jejuni is well adapted to life in the intestines of animals -- and humans -- so it is surprising that it is able to survive on the surface of meat, which is generally stored in ...

Molecular basis for Pseudomonas aeruginosa persistent infections in CF patients

March 12, 2010
New research reveals Small Colony Variants (SCVs) of P. aeruginosa to be a hallmark of chronic infection in cystic fibrosis (CF) patients. Results, published March 12th in the open-access journal PLoS Pathogens, suggest that SCV-mediated persistence might be a good target for antimicrobial chemotherapy.

Molecular basis for Pseudomonas aeruginosa persistent infections in CF patients

March 11, 2010
New research reveals Small Colony Variants (SCVs) of P. aeruginosa to be a hallmark of chronic infection in cystic fibrosis (CF) patients. Results, published March 12 in the open-access journal PLoS Pathogens, suggest that SCV-mediated persistence might be a good target for antimicrobial chemotherapy.