Individuals with major depressive disorder (MDD) often undergo multiple courses of antidepressant treatment during their lives. This is because the disorder can recur despite treatment and because finding the right medication for a specific individual can take time.

If you have a sinus infection, taking a course of antibiotics does not help you recover faster or reduce symptoms any more effectively than taking an inactive placebo, according to a new study by Washington University School of Medicine in St. Louis, Missouri, USA, that is published in ...

Women who took pomegranate seed oil pills to relieve symptoms of the menopause, such as hot flashes, were found to receive no significantly better benefits than those who were given a placebo pill which contained sunflower oil, researchers from the Medical University of Vienna wrote in the journal Menopause. The ...

Researchers involved with a multi-armed clinical trial designed to evaluate different antiretroviral (ARV) interventions for HIV prevention on Friday announced the arm testing a vaginal gel had been stopped because it was not working, the New York Times reports.

A large-scale clinical trial evaluating whether daily use of an antiretroviral-containing oral tablet or vaginal gel can prevent HIV infection in women is being modified because an interim review found that the gel, an investigational microbicide, was not effective among study participants. On Nov...

An independent review of the VOICE study, funded by the National Institute of Allergy and Infectious Diseases (NIAID) and conducted by the Microbicide Trials Network, determined that tenofovir gel was no more effective than placebo gel in preventing HIV.

A recent study has found that PROMETAT, a popular but controversial treatment for methamphetamine addiction, is no more effective than placebo in reducing methamphetamine use, keeping users in treatment, or reducing cravings for methamphetamine.

Abbott announced results from the Phase 3 ABILITY-1 study of HUMIRA® (adalimumab) in patients with active non-radiographic axial spondyloarthritis (axSpA) at the American College of Rheumatology Annual Scientific Meeting (ACR) in Chicago. HUMIRA (adalimumab) is a prescription medicine designed to reduce signs and symptoms of ankylosing spondylitis in adults. ...

A male with an enlarged prostate that causes urinary symptoms does not appear to benefit from higher dosages of saw palmetto, a fruit extract said to help in such cases, researchers from Massachusetts General Hospital, Boston, USA, reported in JAMA (Journal of the American Medical Association). The authors wrote: ...

Saw palmetto, a widely used herbal dietary supplement, does not reduce urinary problems associated with prostate enlargement any better than a placebo, according to research funded by the National Institutes of Health. The study was published Sept. 28 in the Journal of the American Medical Association . ...

(NIH/National Institute of Diabetes and Digestive and Kidney Diseases) Saw palmetto, a widely used herbal dietary supplement, does not reduce urinary problems associated with prostate enlargement any better than a placebo, according to research funded by the National Institutes of Health. The study was published Sept. 28 in the Journal ...

Results from a new sub-analysis of the EMPHASIS-HF study showed significant reductions in death and hospitalization for five pre-defined high-risk patient sub-groups with chronic heart failure (CHF) and mild symptoms treated with eplerenone in addition to standard therapy versus those treated with placebo and standard therapy...