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Posts tagged: nsclc

Daiichi Sankyo, ArQule complete enrollment in tivantinib plus erlotinib Phase 3 NSCLC trial

May 19, 2012
ArQule, Inc. and Daiichi Sankyo, Co., Ltd. today announced that recruitment of patients has been completed in the randomized, double-blind, controlled Phase 3 MARQUEE pivotal trial of their investigational selective c-MET inhibitor, tivantinib, in combination with erlotinib in previously treated patients with locally advanced or metastatic, non-squamous, non-small cell lung ...

Combination of Velcade and Fasudil could treat NSCLC

April 27, 2012
A common cancer drug and a drug used for a rare condition affecting the heart could together treat an aggressive form of lung cancer called non-small cell lung cancer (NSCLC), according to a study published in Cell today.

VeriStrat test may be useful for NSCLC clinical decision-making

April 21, 2012
Results from the combined analysis of two European Phase II trials were presented today at the 3rd European Lung Cancer Conference in Geneva, Switzerland. The VeriStrat retrospective analysis was performed on serum samples from advanced non-squamous non-small cell lung cancer (NSCLC) patients treated with the combination therapy bevacizumab plus ...

NSCLC patients with EGFR mutations benefit from erlotinib-first regimen

April 19, 2012
Patients with advanced non-small cell lung cancer should only receive treatment with the drug erlotinib before receiving standard chemotherapy if their tumor is known to harbor EGFR mutations, researchers report at the 3rd European Lung Cancer Conference in Geneva, Switzerland.

Vaccine Yielded Encouraging Long-Term Survival Rates In Certain Patients With NSCLC

April 9, 2012
Long-term follow-up of a phase II clinical trial showed encouraging survival in some patients with stage 3B/4 non-small cell lung cancer treated with belagenpumatucel-L, a therapeutic vaccine. The findings were presented at the AACR Annual Meeting 2012. "This is a novel immunotherapy that appears to show unusually long survival in ...

Drug Combination May Provide Option To Patients With NSCLC Ineligible For Bevacizumab

April 5, 2012
A combination of nab-paclitaxel and carboplatin for the treatment of non-small cell lung cancer may be a promising option for patients ineligible for treatment with bevacizumab, according to data presented at the AACR Annual Meeting 2012, March 31 - April 4. "The combination of carboplatin and nab-paclitaxel demonstrates promising efficacy ...

Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC

April 4, 2012
CHICAGO Long-term follow-up of a phase II clinical trial showed encouraging survival in some patients with stage 3B/4 non-small cell lung cancer treated with belagenpumatucel-L, a therapeutic vaccine. The findings were presented here at the AACR Annual Meeting 2012, held March 31 - April 4. ...

Drug combination may provide option to patients with NSCLC ineligible for bevacizumab

April 3, 2012
(American Association for Cancer Research) Nab-paclitaxel and carboplatin yielded a 41 percent response rate. Toxicity of the combination is “tolerable.”

CYFRA21-1 might be predictive marker in advanced NSCLC

March 15, 2012
DENVER Researchers found that CYFRA and change in levels of CYFRA were found to be reliable markers for response to chemotherapy for non-small cell lung cancer (NSCLC) in a study of 88 patients. Research presented in the April 2012 issue of the International Association for the Study of Lung ...

CYFRA21-1 might be predictive marker in advanced NSCLC

March 15, 2012
(International Association for the Study of Lung Cancer) Researchers found that CYFRA and change in levels of CYFRA were found to be reliable markers for response to chemotherapy for non-small cell lung cancer in a study of 88 patients. Research presented in the April 2012 issue of the International Association ...

Agennix, DSM sign new contract to manufacture talactoferrin for NSCLC

March 13, 2012
DSM Pharmaceutical Products, the custom manufacturing business of Royal DSM N.V., and Agennix AG have signed a new contract under which DSM will continue to manufacture talactoferrin for Agennix at commercial levels.

PORT may not prolong life in older people with NSCLC

February 13, 2012
Researchers from Mount Sinai School of Medicine have found that post-operative radiation therapy (PORT), a controversial yet frequently administered treatment for lung cancer, may not prolong life in older people with locally advanced disease.