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Posts tagged: mice

Scientists study organ development in mice to unravel how breast cancers develop in people

February 8, 2012
Reviving a theory first proposed in the late 1800s that the development of organs in the normal embryo and the development of cancers are related, scientists at the Salk Institute for Biological Studies have studied organ development in mice to unravel how breast cancers, and perhaps other cancers, develop in ...

Without second wave of brown fat, young mice can’t live without mama

February 7, 2012
For all those who have wondered where they'd be without their mothers, a study reported in the February Cell Metabolism puts a whole new spin on the question. Mice whose mothers pass along a mutant copy of a single imprinted gene can't keep themselves warm and die soon after leaving ...

Researchers Find Additional Benefits Of Cord Blood Cells In Mice Modeling ALS

February 7, 2012
Repeated, low-dose injections of mononuclear cells derived from human umbilical cord blood (MNC hUCB, tradename: U-CORD-CELL™) have been found effective in protecting motor neuron cells, delaying disease progression and increasing lifespan for mice modeling amyotrophic lateral sclerosis, or ALS, also referred to as Lou Gehrig's disease, report University of South ...

Low-dose MNC hUCB therapy effective in ALS-modeled mice

February 7, 2012
Repeated, low-dose injections of mononuclear cells derived from human umbilical cord blood have been found effective in protecting motor neuron cells, delaying disease progression and increasing lifespan for mice modeling amyotrophic lateral sclerosis, or ALS, also referred to as Lou Gehrig's disease, report University of South Florida researchers and colleagues ...

Researchers find additional benefits of cord blood cells in mice modeling ALS

February 6, 2012
Repeated, low-dose injections of mononuclear cells derived from human umbilical cord blood (MNC hUCB, tradename: U-CORD-CELL) have been found effective in protecting motor neuron cells, delaying disease progression and increasing lifespan for mice modeling amyotrophic lateral sclerosis, or ALS, also referred to as Lou Gehrig's disease, report University of South ...

Neurons from stem cells could replace mice in botulinum test

February 6, 2012
(PhysOrg.com) -- Using lab-grown human neurons, researchers from the University of Wisconsin-Madison have devised an effective assay for detecting botulinum neurotoxin, the agent widely used to cosmetically smooth the wrinkles of age and, increasingly, for an array of medical disorders ranging from muscle spasticity to loss of bladder control.

USF and Saneron researchers find additional benefits of cord blood cells in mice modeling ALS

February 3, 2012
(University of South Florida (USF Health)) Repeated, low-dose injections of mononuclear cells derived from human umbilical cord blood were effective in protecting motor neuron cells, delaying disease progression and increasing lifespan for mice modeling amyotrophic lateral sclerosis, or ALS, also referred to as Lou Gehrig's disease. The findings are reported ...

Improved Kidney Transplant Survival In Mice; New Agent Likely To Speed Replacement Of Other Organs

February 1, 2012
New research published online in the FASEB Journal details a new antibody, called "OPN-305" that may significantly improve survival outcomes for those receiving donated kidneys and other organs. OPN-305 works by preventing inflammation triggered by oxygen deprivation in the donated organ, allowing for better recovery after transplantation. Specifically, it binds ...

Cancer drugs shown to cause mutations in mice offspring

January 31, 2012
(Medical Xpress) -- For many years, most of the studies done to see what effects cancer treatment has on the offspring of survivors, has involved radiation. This is because radiation is known to cause mutations in cells. Not so well studied have been the generational effects of chemicals used to ...

New agent improves kidney transplant survival in mice, likely to speed replacement of other organs

January 31, 2012
New research published online in the FASEB Journal details a new antibody, called "OPN-305" that may significantly improve survival outcomes for those receiving donated kidneys and other organs. OPN-305 works by preventing inflammation triggered by oxygen deprivation in the donated organ, allowing for better recovery after transplantation. Specifically, it binds ...

New agent improves kidney transplant survival in mice, likely to speed replacement of other organs

January 31, 2012
(Federation of American Societies for Experimental Biology) New research published online in the FASEB Journal details a new antibody, called "OPN-305" that may significantly improve survival outcomes for those receiving donated kidneys and other organs.

Tiny crooners: Male house mice sing songs to impress the girls

January 26, 2012
It has been known for some time that house mice ( Mus musculus ) produce ultrasonic vocalizations (USVs) during courtship but it has generally been assumed that these are no more than squeaks. However, recent spectrographic analyses have revealed that USVs are complex and show features of song. Although ...