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Posts tagged: gene

CD97 gene expression and function correlate with WT1 protein expression and glioma invasiveness

February 7, 2012
Researchers at Virginia Commonwealth University Medical Center's VCU Massey Cancer Center and Harold F. Young Neurosurgical Center (Richmond, VA) and Old Dominion University (Norfolk, VA) have discovered that suppression of Wilms tumor 1 protein (WT1) results in downregulation of CD97 gene expression in three glioblastoma cell lines and reduces the ...

In autism, gene findings may help explain biology, guide drug discovery

February 7, 2012
(Medical Xpress) -- Autism and related disorders that profoundly affect behavior and development are diagnosed more often today than ever before.

Clues To Common Birth Defect Found In Gene Expression Data

February 7, 2012
Researchers at MassGeneral Hospital for Children (MGHfC), The Jackson Laboratory and other institutes have uncovered 27 new candidate genes for congenital diaphragmatic hernia (CDH), a common and often deadly birth defect. Their sophisticated data-filtering strategy, which uses gene expression during normal development as a starting point, offers a new, efficient ...

CD97 gene expression and function correlate with WT1 protein expression and glioma invasiveness

February 7, 2012
(Journal of Neurosurgery Publishing Group) Researchers at Virginia Commonwealth University and Old Dominion University have discovered that suppression of Wilms tumor 1 protein (WT1) results in downregulation of CD97 gene expression in three glioblastoma cell lines and reduces the characteristic invasiveness exhibited by glial tumor cells. This finding is published ...

Gene mutation discovery sparks hope for effective endometriosis screening

February 7, 2012
Researchers at Yale School of Medicine have, for the first time, described the genetic basis of endometriosis, a condition affecting millions of women that is marked by chronic pelvic pain and infertility. The researchers' discovery of a new gene mutation provides hope for new screening methods.

Scientists search gene alterations in three-parent kids

February 6, 2012
Researchers from Australia want to find out if using the DNA of three parents will prevent children inheriting life-threatening diseases. They add that if the technique proves successful in preventing the transfer of mitochondrial DNA mutations from mothers to babies, then laws on the use of embryos will need to ...

Researchers find clues to common birth defect in gene expression data

February 6, 2012
Researchers at MassGeneral Hospital for Children (MGHfC), The Jackson Laboratory and other institutes have uncovered 27 new candidate genes for congenital diaphragmatic hernia (CDH), a common and often deadly birth defect.

Gene mutation discovery sparks hope for effective endometriosis screening

February 6, 2012
Researchers at Yale School of Medicine have, for the first time, described the genetic basis of endometriosis, a condition affecting millions of women that is marked by chronic pelvic pain and infertility. The researchers' discovery of a new gene mutation provides hope for new screening methods. Published ...

Controlling Gene Expression With New RNA-Based Therapeutic Strategies

February 6, 2012
Small RNA-based nucleic acid drugs represent a promising new class of therapeutic agents for silencing abnormal or overactive disease-causing genes, and researchers have discovered new mechanisms by which RNA drugs can control gene activity. A comprehensive review article in Nucleic Acid Therapeutics, a peer-reviewed journal published by Mary Ann Liebert, ...

Gene Related To Fat Preferences In Humans Found

February 6, 2012
A preference for fatty foods has a genetic basis, according to researchers, who discovered that people with certain forms of the CD36 gene may like high-fat foods more than those who have other forms of this gene. The results help explain why some people struggle when placed on a low-fat ...

Gene mutation discovery sparks hope for effective endometriosis screening

February 6, 2012
(Yale University) Researchers at Yale School of Medicine have, for the first time, described the genetic basis of endometriosis, a condition affecting millions of women that is marked by chronic pelvic pain and infertility. The researchers' discovery of a new gene mutation provides hope for new screening methods.

Best Treatment For TB Patients Could Be Determined By ‘Goldilocks’ Gene

February 5, 2012
'Tuberculosis patients may receive treatments in the future according to what version they have of a single 'Goldilocks' gene, says an international research team from Oxford University, King's College London, Vietnam and the USA. This is one of the first examples in infectious disease of where an individual's genetic profile ...