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Posts tagged: development

Mutation Found In Half Of All Prostate Cancers May Lead To Disease Development And Other Cancers

May 24, 2012
Up to half of all prostate cancer cells have a chromosomal rearrangement that results in a new "fusion" gene and formation of its unique protein - but no one has known how that alteration promotes cancer growth. Now, Weill Cornell Medical College researchers have found that in these cancer cells, ...

Scientists identify key mechanism in development of Alzheimer’s

May 23, 2012
New research by scientists at the University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine (UMDNJ-SOM) demonstrates how dying or damaged brain cells release debris into the bloodstream and give rise to specific autoantibodies that appear to be reliable biomarkers for early diagnosis of Alzheimer's and other neurodegenerative ...

Scientists trace origin and development of vancomycin-resistant S. aureus

May 23, 2012
National Institutes of Health-funded scientists have determined the genome sequences of a dozen strains of Staphylococcus aureus bacteria known to be resistant to vancomycin, an antibiotic of last resort. The researchers demonstrated -that resistance arose independently in each strain, and identified shared features among the strains that may have helped ...

Newly discovered protein makes sure brain development isn’t ‘botched’

May 21, 2012
(Johns Hopkins Medical Institutions) Johns Hopkins scientists have discovered a protein that appears to play an important regulatory role in deciding whether stem cells differentiate into the cells that make up the brain, as well as countless other tissues. This finding, published in the April Developmental Cell, could eventually shed ...

Sigmoid provides financial and product development update

May 19, 2012
Sigmoid Pharma Ltd., a privately-owned, specialty pharmaceutical and drug delivery company registered in Ireland, today provides an update on significant progress in 2011 and 2012.

Agfa HealthCare opens state-of-the-art, worldwide R&D facility for clinical imaging IT solutions development

May 17, 2012
Facility is a center of excellence for the design of innovative solutions that will bring further revolutionary developments for radiology, pathology and healthcare delivery as a whole to image-enable the Electronic Health Record (EHR)

Untangling the development of breast cancer

May 17, 2012
(Wellcome Trust Sanger Institute) The team created a catalog of all the mutations in the genomes of the 21 breast cancer genomes. They identified entirely new mutational processes that drive breast cancer development, including one remarkable process defined by localized regions of hypermutation found in most of the breast cancers. ...

Plant growth without light control: Synthetic photoreceptor stimulates germination and development

May 16, 2012
Plants are dependent on the sun. Sunlight does not only supply them with energy, but also controls their development steps. So-called photoreceptors activate the processes of germination, leaf development, bud formation, and blossoming in the cells. The light-absorbing component of a photoreceptor may be replaced by a chemically similar synthetic ...

Different Mechanisms Of Pain Discovered Which Suggest New Strategies For Drug Development

May 15, 2012
Researchers at the University of Leeds have found a previously unknown mechanism through which pain is signalled by nerve cells - a discovery that could explain the current failings in the drug development process for painkillers and which may offer opportunities for a new approach...

As MDGs set to expire in 2015, U.N. panel to advise on approaches to development; African Progress Panel calls for ‘big push’ on continent

May 15, 2012
"The presidents of Indonesia and Liberia -- Susilo Bambang Yudhoyono and Ellen Johnson Sirleaf -- and the prime minister of the United Kingdom, David Cameron, are to co-chair a U.N. panel to advise on approaches to development after the Millennium Development Goals (MDGs) expire in 2015," SciDev.Net reports.

Understanding the RNAi Reagents Market Overlap with Drug Discovery and Therapeutic Development is Critical for Pharmaceutical Leaders

May 14, 2012
FARMINGTON, Conn., May 14, 2012 /PRNewswire-iReach/ -- Global Information Inc. is pleased to announce two significant new reports on RNA interference (RNAi) and its relationship with peripheral markets: RNA Interference (RNAi) Global Industry Analysts' new RNA Interference (RNAi) market research report ...

mTOR protein plays a key role in development of diabetes

May 14, 2012
The signaling protein mTOR is a key regulator that controls cell growth. Dysfunction of mTOR increases not only the likelihood of developing cancer but also diabetes. In the current issue of the journal Cell Metabolism, Mike Hall and his team from the Biozentrum of the University of Basel describe how ...