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Posts tagged: breast

Preliminary results from Celldex’s CDX-011 Phase 2b breast cancer study

May 24, 2012
Celldex Therapeutics, Inc. today announced preliminary results from the Company's randomized Phase 2b EMERGE study of CDX-011 (glembatumumab vedotin) antibody drug conjugate in patients with glycoprotein NMB (GPNMB) expressing, advanced, heavily pretreated breast cancer. Preliminary results suggest that CDX-011 induces impressive response rates compared to current, available therapies in patients ...

MTI develops SureTouch Wireless system for breast cancer screening

May 23, 2012
Medical Tactile, Inc. (MTI), with the support of The Pre-Mammogram Foundation and Qualcomm Incorporated, today announced that they have developed a pre-commercial SureTouch Wireless system that uses 3G-enabled tactile sensor technology for breast cancer screening.

New clinical trial to evaluate HSP90 inhibitor plus hormonal therapy for breast cancer

May 23, 2012
Pushed to the brink of survival, the hyper-driven cells of a cancerous tumor tap into an ancient system that has helped organisms cope with internal stresses and environmental challenges since life began. As an integral part of this system, heat shock protein 90 (HSP90) has been shown to help malignant ...

Discovery Suggests New Combination Therapy Strategy For Basal-Like Breast Cancers

May 23, 2012
Multiple research projects - including a 2006 study conducted at the University of North Carolina at Chapel Hill - have used DNA microarray analysis to identify several breast cancer subtypes, including luminal A, luminal B, basal-like and HER2-enriched. Simple tests are being developed to help doctors identify these subtypes and ...

Levels Of Sex Hormones Linked To Breast Cancer Risk Reduced By Moderate Weight Loss

May 23, 2012
Even a moderate amount of weight loss can significantly reduce levels of circulating estrogens that are associated with an increased risk of breast cancer, according to a study by researchers at Fred Hutchinson Cancer Research Center - the first randomized, controlled clinical trial to test the effects of weight loss ...

B cells in breast milk can produce HIV-neutralizing antibodies

May 23, 2012
Antibodies that help to stop the HIV virus have been found in breast milk. Researchers at Duke University Medical Center isolated the antibodies from immune cells called B cells in the breast milk of infected mothers in Malawi, and showed that the B cells in breast milk can generate neutralizing ...

Breast MRI helps predict chemotherapy’s effectiveness

May 23, 2012
(Radiological Society of North America) MRI provides an indication of a breast tumor's response to pre-surgical chemotherapy significantly earlier than possible through clinical examination, according to a new study.

Cardio fitness levels of breast cancer patients may affect survival

May 23, 2012
(Duke University Medical Center) Women receiving care for breast cancer have significantly impaired cardio-pulmonary function that can persist for years after they have completed treatment, according to a study led by scientists at Duke University Medical Center.

Newly discovered breast milk antibodies help neutralize HIV

May 22, 2012
DURHAM, N.C. Antibodies that help to stop the HIV virus have been found in breast milk. Researchers at Duke University Medical Center isolated the antibodies from immune cells called B cells in the breast milk of infected mothers in Malawi, and showed that the B cells in breast milk ...

Breast MRI helps predict chemotherapy’s effectiveness

May 22, 2012
OAK BROOK, Ill. Magnetic resonance imaging (MRI) provides an indication of a breast tumor's response to pre-surgical chemotherapy significantly earlier than possible through clinical examination, according to a new study published online in the journal Radiology . Women with breast cancer often undergo chemotherapy ...

Breast cancer clinical trial tests combo of heat shock protein inhibitor and hormonal therapy

May 22, 2012
CAMBRIDGE, Mass. (May 22, 2012) Pushed to the brink of survival, the hyper-driven cells of a cancerous tumor tap into an ancient system that has helped organisms cope with internal stresses and environmental challenges since life began. As an integral part of this system, heat shock protein 90 ...

HDAC Inhibitor Targets Triple Negative Breast Cancer

May 22, 2012
The histone de-acetylase (HDAC) inhibitor panobinostat is able to target and destroy triple negative breast cancer, reveals a new study published in BioMed Central's open access journal Breast Cancer Research. Researchers from Tulane University Health Sciences Center have shown that panobinostat was able to destroy breast cancer cells and reduce ...