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Directly observed HIV treatment by patient-nominated treatment supporter improves survival

June 11, 2010
When applied to HIV care, the community-based model of directly observed therapy (DOT) has no effect on virologic outcomes, but significantly improves patient survival. This is according to researchers at the Johns Hopkins Bloomberg School of Public Health, in collaboration with colleagues at University of Cape Town, South Africa, who conducted the first randomized controlled trial of patient-nominated treatment-supporters providing partial DOT in resource-limited settings. The researchers found that mortality rates were lower among DOT patients than among self-monitored antiretroviral therapy (ART). The results are featured in the June 1, 2010, issue of AIDS.

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