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Category: Colorectal Cancer

A Viable Way For Colorectal Cancer Patients To Overcome Drug Resistance

April 9, 2012
When combined with other treatments, the drug cetuximab - which works by slowing or stopping the growth of cancer cells - has been shown to extend survival in certain types of cancer, including metastatic colorectal cancers. Unfortunately, about 40 percent of colorectal cancer patients - specifically those who carry a ...

Embarrassment, Social Stigma May Discourage Obese White Women From Seeking Colon Cancer Screening

April 8, 2012
A new study by Johns Hopkins researchers shows that obese white women may be less likely than normal-weight counterparts and African-Americans of any weight or gender to seek potentially lifesaving colon cancer screening tests. Results of this study follow the same Johns Hopkins group's previous research suggesting that obese white ...

Targeted Therapeutics For Colon Cancer

April 6, 2012
Anurag Singh, PhD, assistant professor in the Department of Pharmacology and Experimental Therapeutics at Boston University School of Medicine presented his recent work on targeted therapeutics for colon cancer at the American Association of Cancer Research Annual Meeting in Chicago, IL. Singh's seminar. It was featured in the "Late-Breaking Abstracts ...

Cetuximab After Colon Cancer Surgery – No Improvement In Disease-Free Survival

April 5, 2012
A study published in the April 4 issue of JAMA reveals that patients who receive the drug cetuximab in addition to chemotherapy after undergoing surgery for stage III colon cancer do not have improved disease-free survival. According to the researchers, the chance of cure among patients who ...

Colorectal Cancer: Noninvasive Stool Test Unaffected By Medications, Lifestyle Factors And Other Variables

April 5, 2012
Research on an investigational DNA methylation test for colorectal cancer demonstrated that the only clinical variable that influenced test results was age, according to results presented at the AACR Annual Meeting 2012, March 31 - April 4. "There was a progressive increase in background methylation levels that varied widely between ...

Stem Cells From Intestinal Crypt Lead Researchers To Cancer Discovery

April 3, 2012
Tales from the crypt are supposed to be scary, but new research from Vanderbilt University, the HudsonAlpha Institute for Biotechnology and colleagues shows that crypts can be places of renewal too: intestinal crypts, that is. Intestinal crypts are small areas of the intestine where new cells are formed to continuously ...

Seeking Clues To Colon Cancer In Newly Identified Stem Cells

April 2, 2012
Vanderbilt-Ingram Cancer Center researchers have identified a new population of intestinal stem cells that may hold clues to the origin of colorectal cancer. This new stem cell population, reported in the journal Cell, appears to be relatively quiescent (inactive) - in contrast to the recent discovery of intestinal stem cells ...

Pre-Cancerous Polyps May Be Hidden When Bowel Prep Inadequate Prior To Colonoscopy

March 29, 2012
What happens on the day before a colonoscopy may be just as important as the colon-screening test itself. Gastroenterologists at Washington University School of Medicine in St. Louis have found that when patients don't adequately prep for the test by cleansing their colons, doctors often can't see potentially dangerous pre-cancerous ...

Colorectal Cancer Screening Rates Shown To Be High In Patients With Multiple Health Problems

March 22, 2012
A study by University of Kentucky researchers showed that in Appalachia, colorectal cancer screening rates were higher in the population with multiple morbidities or diseases compared to those who had no morbidities at all. Published in the Southern Medical Journal, the study used data based on a survey of 1,153 ...

Obesity Increases The Risk For Colorectal Cancer And Polyps

March 16, 2012
The American College of Gastroenterology (ACG) and the Campaign to End Obesity (CEO) are joining forces to highlight the potentially deadly link between higher Body Mass Index (BMI) and colorectal cancer. In light of the increasing prevalence of obesity in the United States and the strength of the scientific evidence ...

Worries About Quality Of Colon Cancer Screening Follow Pressures To Increase Volume Of Colonoscopies

March 13, 2012
Researchers at Mount Sinai School of Medicine have found that 92 percent of more than 1,000 gastroenterologists responding to a survey believed that pressures to increase the volume of colonoscopies adversely impacted how they performed their procedures, which could potentially affect the quality of colon cancer screening. The findings, based ...

Colorectal Cancer For Under 50s On The Rise

March 13, 2012
Whilst colorectal cancer cases are generally on the decline since the beginning of the millennium, there seems to be an alarming rise in those under 50 hit by the disease. Since 1992, the number of people diagnosed with colorectal cancer has risen by two percent per year. One example, given ...